![]() ![]() ![]() If your symptoms are more severe, you may need additional treatments such as painkillers and a structured exercise plan with a physiotherapist. using special devices to reduce the strain on your joints during your everyday activities.Mild symptoms can sometimes be managed with simple measures, including: A number of treatments are also available to reduce the symptoms. Osteoarthritis is a long-term condition and cannot be cured, but it doesn't necessarily get any worse over time and it can sometimes gradually improve. For example, prolonged joint stiffness in the morning can be a sign of rheumatoid arthritis.įurther tests – such as X-rays or blood tests – are not usually necessary, but may be used to rule out other possible causes, such as rheumatoid arthritis or a fractured bone. If your symptoms are slightly different, this may indicate another joint condition. the stiffness in your joints is not there in the mornings, or lasts less than 30 minutes.you have joint pain that gets worse the more you use your joints.To help determine whether you have osteoarthritis, a GP will first ask you about your symptoms and examine your joints. being a woman – osteoarthritis is more common in women than men.obesity – being obese puts excess strain on your joints, particularly those that bear most of your weight, such as your knees and hips.family history – osteoarthritis may run in families, although studies have not identified a single gene responsible.age – your risk of developing the condition increases as you get older.other conditions (secondary arthritis) – osteoarthritis can happen in joints severely damaged by a previous or existing condition, such as rheumatoid arthritis or gout.joint injury – overusing your joint when it has not had enough time to heal after an injury or operation.The exact cause is not known, but several things are thought to increase your risk of developing osteoarthritis, including: ![]() (Redness can be harder to see on brown and black skin.) Bony growths can develop, and the area can become swollen and red. In most cases, your body repairs the damage itself and you do not experience any symptoms.īut in osteoarthritis, the protective cartilage on the ends of your bones breaks down, causing pain, swelling and problems moving the joint. Causes of osteoarthritisĪs part of normal life, your joints are exposed to a constant low level of damage. Read more about the symptoms of osteoarthritis. You should see your GP if you have persistent symptoms of osteoarthritis so they can confirm the diagnosis and prescribe any necessary treatment. Other people can experience more continuous and severe problems which make it difficult to carry out everyday activities.Īlmost any joint can be affected by osteoarthritis, but the condition most often causes problems in the knees, hips and small joints of the hands. The severity of osteoarthritis symptoms can vary greatly from person to person, and between different affected joints.įor some people, the symptoms can be mild and may come and go. grating or crackling sound when moving the affected joints.The main symptoms of osteoarthritis are joint pain and stiffness, and problems moving the joint. It's the most common type of arthritis in the UK. Demonstrating that the subchondral bone plays a role in the initiation of OA would greatly contribute to furthering our knowledge of this pathology and provide new insights for therapeutic approaches.Osteoarthritis is a condition that causes joints to become painful and stiff. Potential candidates include insulin-like growth factor-1 (IGF-1), transforming growth factor-β (TGF-β) interleukin 1β (IL-1β), and interleukin-6 (IL-6). Therefore, it is possible that certain bone-derived products drive cartilage metabolism. Interestingly, studies have shown the presence of clefts or channels in the tidemark that appears early in OA, indicating a possible way to traffic cytokines and growth factors from the subchondral compartment to the overlying cartilage. Indeed, the subchondral bone tissue produces a number of similar proinflammatory cytokines, and growth factors are involved in cartilage tissue remodeling. Recent evidence suggests a key role for the subchondral bone tissue in the progression and/or initiation of OA. However, it has been suggested that increased catabolism due to elevated cytokines and growth factors in OA joints plays a significant role. We still do not completely understand what initiates the degradation and loss of cartilage. Abstract Osteoarthritis (OA) is considered to be a complex illness in which the tissues of the joint play a significant role in the initiation and/or progression of the pathophysiology. ![]()
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